2nd Edition of World Nanotechnology Conference

April 27-29, 2020 | Baltimore, USA

Crowne Plaza Hotel Baltimore Dowtown –
Inner Harbor, 105 W Fayette Street
Baltimore, MD 21201 USA
Phone : 1 (702) 988 2320
Toll Free: 1800–883-8082
Whatsapp: +1 (540) 709-1879
Email: worldnano@magnus-group.org
April 27-29, 2020 | Baltimore, USA

Rania Karas

Speaker for Nanomaterials Conferences
Rania Karas
Nile Pack, Egypt
Title : Anti-aging effects of a novel nano-composite on human dermal fibroblasts cells

Abstract:

This work mainly aimed to produce and characterize a nano-composite depends on ascorbic acid (AA) as an active ingredient. The new composite has anti-aging potential and high stability profile. The cytotoxic effects and the proliferation rate of the new composite were investigated on adult human dermal fibroblasts cells. This composite is using nano-hydroxyapatite (nHAp) as a vehicle for delivering AA. nHAp was an ideal candidate for the suggested model due to its exceptional biocompatibility, bioactivity and not exhibiting cytotoxic effects. A mixture of vitamin E (vit E) and frankincense oil (Fk O) has been suggested as a protective coating matrix for AA. nHAp nano-powder was obtained via the wet chemical precipitation reaction. Clear solution of nHAp was prepared at both lower and higher reactions temperature. The proliferation rate of cultured dermal fibroblasts cells was evaluated and compared to no treated control which showed higher proliferation rate in the samples treated with the new composite AA- vit E- Fk O - nHAp. The stability against sunlight and heat was performed in which AA- vit E- Fk O- nHAp composite showed stability against sunlight and heat. The physico-chemical properties of nano- vehicle (nHAp) were characterized by XRD, FTIR and EDX. The size and morphology of the new composite were characterized by TEM. AA-vit E- Fk O - nHAp is expected to have great skin rejuvenation potential due to having a higher proliferative capacity for the dermal  fibroblasts cells than AA.

Biography:

Rania Alfy Ayad Karas was born in Menia in Upper Egypt. I am pure Coptic (the Copts are the true descendants of the Ancient Egyptians). Currently, I run my family business as I am the general manger of Nile Pack Company but this couldn't stop my passion to science and led me to construct R&D department in our company. My Education BSc in Science Biology. Faculty of Science - Menia University. (2007) Diploma in Laser Sciences , Department of laser applications in Photochemistry, Photobiology and Agriculture (LAMPA) – The National Institute of Laser Enhanced Sciences (NILES) - Cairo University. (2011) MSc in Laser Applications in Photochemistry and Photobiology. Department of laser applications in Photochemistry, Photobiology and Agriculture (LAMPA) – The National Institute of Laser Enhanced Sciences (NILES) - Cairo University. (2016) 
 

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