HYBRID EVENT: You can participate in person at Singapore or Virtually from your home or work.

8th Edition of World Nanotechnology Conference

March 18-20, 2024

March 18 -20, 2024 | Singapore
World Nano 2024

Akanksha Awadhesh Singh

Akanksha Awadhesh Singh, Speaker at Nanoscience Conferences
Rashtrasant Tukadoji Maharaj Nagpur University, India
Title : Pivotal involvement of CD-36 mediated VAV protein acts like a catalyst in the interplay between the macrophages and graphene nanoplatelets


CD-36 is known to play a key role in mediating the interaction between the macrophages and graphene nanoplatelets. Graphene nanoplatelets are arranged in the stacks of graphene in a planarly in a two-dimensional manner with an average length and thickness in the microns. The VAV is known to be a key regulator allowing the CD-36 to form the foam cells due to excessive lipid content in the macrophages. The CD-36 molecules are also known to increase the lipidity of the cells thus making the macrophages competent in the cellular metabolism. It has been found that the higher levels of CD-36 are known to accelerate the interaction between the macrophages and graphene nanoplatelets. So, what might be possible molecule behind this? Is the VAV is main agent behind the activity of the CD-36? As the VAV works in the coordination with Ca2+ molecules for the better function of the CD-36, so it might be possible that modifications in the VAV protein with the aid of the CRISPR Cas-9 proteins can lead to inhibited activity of the CD-36 protein that will supress the interaction between the graphene nanoplatelets and macrophages. This review analyses the regulated activity of the CD-36 molecules in the orchestrated interplay between the mouse-induced macrophages and the graphene nanoplatelets. 

Audience Take Away:

  • Graphene nanoplatelets has already been rewarded by the scientific industry due to numerous benefits but the lesser facts are known about how does the macrophages are interacted with the graphene nanoplatelets and how they both react in the presence of CD-36


Miss Akanksha Awadhesh Singh is a biotechnologist and a content editor by profession. With a strong background in biotechnology, she is becoming really passionate about the understanding the molecular mechanisms involved behind the interaction of pathogens with the immune cells in greater detail. She has written several research and review papers in many International journals and had even written a newsletter for the GET consortium, South Africa. She is also a poetess who has published her poetry journal “Ehsaas” now available at Amazon and even a blogger in the health and wellness niche at Medium.com.