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10th Edition of World Nanotechnology Conference

March 10-12, 2025

March 10 -12, 2025 | Rome, Italy
World Nano 2021

Preparation of invasomes -A novel carrier for drug delivery

Abbaraju Krishna Sailaja, Speaker at Nanoscience Conferences
RBVRR Women’s College of Pharmacy, India
Title : Preparation of invasomes -A novel carrier for drug delivery


Background: Diclofenac sodium is capable of providing benefit to patients suffering from: rheumatoid arthritis, osteoarthritis, and gout. Diclofenac sodium is a medicine that reduces inflammation and pain. It is also used to treat aches and pains, as well as problems with joints, muscles, and bones. The aim of the present work is to prepare diclofenac sodium invasomes by thin film hydration technique.

Methodology: In the present study, for the preparation of diclofenac sodium loaded invasomes by thin film hydration technique. The obtained formulations were studied for characterization and evaluation parameters.

Results: Among all three formulationsF1 formulation prepared by using 1:1 ratio of drug and lipid at 400 rpm was showing promising results with drug content as 52.51% and drug release of 72.48% were able to sustain the drug release for 12 hours. Conclusions: In this study diclofenac sodium invasomes were prepared by thin film hydration method by using soya lecithin as lipid and using span 60 as surfactant. This study was performed to determine parameters such as drug content and drug release. F1 formulation was considered as the best formulation as it shown best and promising results.


Dr. A. Krishna Sailaja is currently working as Associate Professor and Head of the Department in RBVRR Women’s college of pharmacy, Osmania University, Hyderabad. She has published 130 research papers in various National and International journals. She delivered more than 25 talks on novel drug delivery systems. Published 5 books and filed 4 patents.