HYBRID EVENT: You can participate in person at Orlando, USA or Virtually from your home or work.

6th edition of World Nanotechnology Conference

April 24-25, 2023

April 24 -26, 2023 | Orlando, USA
World Nano 2022

Delivery of drugs to brain through nasal route

Sanjib Bahadur, Speaker at Nanotechnology conferences
Himalayan Pharmacy Institute, India
Title : Delivery of drugs to brain through nasal route

Abstract:

Despite the fact that the global prevalence of neurologic illnesses is increasing, most medication molecules are still unable to reach the brain in therapeutic amounts. The blood-brain barrier is made up of a thin layer of endothelial cells surrounded by astrocyte foot processes, and these anatomic features act as a considerable impediment to drug transfer from the blood to the brain. Use of the nasal route of administration to deposit medications at the olfactory region of the nares, from where they travel to the brain by methods that are still unknown, with travel via nerve fibres and transport via a perivascular pathway both being suggested. With both fluid and particle formulations, the nose-to-brain pathway has been established frequently in preclinical mice. In human trials using solution and particle formulations, the nose-to-brain pathway has also been demonstrated. With device manufacturers joining the fray, the advantages of this distribution method can be translated into approved devices. The following are the key factors that determine the efficacy of delivery via this route: delivery to the olfactory region of the nares rather than the respiratory region, a longer retention time at the nasal mucosal surface, enhanced penetration of the active through the nasal epithelia, and reduced drug metabolism in the nasal cavity.

Audience take-away:

  • Audience will get to know the
  • Difficulty in brain drug delivery
  • Nasal drug delivery
  • Application of nasal drug delivery for delivering drug to brain

Biography:

Dr. Sanjib Bahadur graduated with a Bachelor in Pharmacy from University of North Bengal, India in 2005 and then he obtained his Masters in Pharmacy from the University of North Bengal, India in 2007. He has completed his PhD from Chhattisgarh Swami Vivekanand Technical University, Bhilai, Chhattisgarh. He has published more than 40 papers published in in various national & international Journals. He has presented many research papers in various conferences. He himself has organized many conferences & seminar. He has worked on number of research projects as Principal Investigator funded by AICTE, New Delhi and CCOST, Raipur. He has filed application for patent. He has contributed in various Journals as Reviewer and Editor. His research interest is formulation and development, Novel Drug Delivery Systems, Controlled Drug Delivery System. He has supervised 22 M. Pharm scholars and at present 4 Ph.D scholars are conducting their research work under his supervision. He has 15 years of teaching and research experience. He has contributed as abstract screener for AAPS Conference organized by American Association of Pharmaceutical Scientists for last three years. Currently he is working as Associate Professor and Head, Department of Pharmaceutics, in Himalayan Pharmacy Institute, Sikkim. 

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