HYBRID EVENT: You can participate in person at Orlando, USA or Virtually from your home or work.

6th edition of World Nanotechnology Conference

April 24-25, 2023

April 24 -26, 2023 | Orlando, USA
World Nano 2022

Self-emulsification systems – A nanotranforming of poor aqueous solubility towards enhanced bioavailaility of drugs

Pragya Baghel, Speaker at Nanotechnology Conferences
Columbia Institute of Pharmacy, India
Title : Self-emulsification systems – A nanotranforming of poor aqueous solubility towards enhanced bioavailaility of drugs

Abstract:

High lipophilicity and poor aqueous solubility are the endemic problems of new drug molecules. 60-70% of these drugs are unable to solubilize completely in aqueous media, or have very low permeability. Oral route has been the major route of drug delivery for the chronic treatment of many diseases as it offers a high degree of patient compliance. Nearly 40% of new drug candidate exhibit low solubility in water. This is a challenge in development of optimum oral solid dosage form in terms of formulation design and bioavailability of new pharmaceutical products, this hampers their oral absorption and further leads to their poor bioavailability. Various researches are in progress to overcome these limitations. Novel Technologies like nano-carrier systems have become popular for improving the solubility of drugs. Lipid based formulations, among nano systems, are taking pace for the enhancement of solubility, oral absorption and hence the bioavailability of drugs. Among the lipid formulations, Self-emulsification systems are gaining popularity by offering various advantages to delivery systems. Self-emulsifying drug delivery systems are isotropic blends of oil and surfactant/co-surfactants, which, upon gentle agitation on watery media shape o/w emulsion.

Audience take-away:

  • Inspite of many works published in SEDDS, the major concerns of this presentation is to discuss about the various approaches to formulate a good lipid based carrier system for poorly aqueous soluble drugs, role of various polymers and their categories used in the formulation along-with the modern technologies used for enhancing the stability of liquid SEDDS.

Biography:

Mrs. Pragya Baghel, is graduated from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh, India, and completed her post-graduation in Pharmaceutics branch from Columbia Institute of Pharmacy, Raipur, Chhattisgarh, India. Right now she is pursuing PhD from Chhattisgarh swami Vivekananda Technical University, Bhilai, Chhattisgarh. Presently she is working as Assistant Professor, Columbia Institute of Pharmacy. She has more than 20 publications. She has conducted one National Conference under the sanctioned authority Chhattisgarh council of science & Technology.

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