HYBRID EVENT: You can participate in person at Orlando, USA or Virtually from your home or work.

6th edition of World Nanotechnology Conference

April 24-25, 2023

April 24 -26, 2023 | Orlando, USA
World Nano 2022

Strategies for enhanced protein nano-engineering with improved stability and activity

Dibyendu Mondal, Speaker at Nanotechnology conferences
Institute of Plant Genetics of the Polish Academy of Sciences (IPG PAS), Poland
Title : Strategies for enhanced protein nano-engineering with improved stability and activity

Abstract:

This talk will be focused on two different topics which are (i) strategies for improving the stability and activity of enzymes for facile biocatalysis and (ii) vision for the department of plant nanotechnology and its proposed structure within the scope of NANOPLANT project funded by the European union. Enzymatic biocatalysis has been recognized as key process applied in diverse  fields  of  applications  including  synthesis  of  valuable  pharmaceutical  intermediates  and biofuels from renewable resources. However, the fact that enzymes have evolved to work in cellular environments and are therefore usually unstable to harsh process conditions such as temperature, pressure, use of organic solvents and etc.—the major barrier to the use of the enzyme in industrial biotechnology. Consequently, there is a clash between low- temperature aqueous processing (optimal conditions for enzyme stability and selectivity), and organic solvent or high-temperature processing (which favours high substrate solubility and immensely improved reaction kinetics, respectively). First part of the talk majorly will focus fundamentals of protein packaging and some of the interesting results that we developed in our laboratory. We developed a facile protocol for sustainable protein packaging platform using biomass derived functional carbon materials as host and also via manipulation of solvent environment using molecularly crowded ionic liquids.

Audience take-away:

  • An alternative protein engineering protocol?
  • How to improve the kinetics of enzymatic biocatalysis under harsh reaction conditions.

Biography:

Dr. Mondal is an ERA chair holder of NANOPLANT in IPG PAS, Poznan, Poland. Dibyendu earned PhD in Chemical Sciences from CSIR-CSMCRI, India in 2015. He was a postdoctoral fellow at CICECO, University of Aveiro, Portugal from 2015-2017 and has been an Assistant Professor at CNMS, Jain University, India since 2017. His research interest include value addition of bio-resources and packaging of biomolecules using green solvents. He is also fascinated with green nanocomposites for task-specific applications such as biocatalysis, water purification and in plant science. He has 70 publications in high impact journals, 5 granted patents, ~2300 citations, 25 h-index.

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