Title : Surface functionalization : A key factor for the synthesis of nanomaterials for applicatory purposes
Abstract:
The ability to modify the surface of nanomaterials by functionalization has steered in a new era in nanotechnology, particularly in the pharmaceutical and biomedical sciences. According to the clinical findings, functionalizing nanoparticles with certain chemical species resulted in multifunctional nanoparticles with improved efficacy. Functionalized nanoparticles that have been precisely created are being used as optical materials, sensor components, catalyst precursors, for targeted drug delivery, and a variety of other applications. In the creation of advanced nano- materials, functionalizing host molecules with inorganic/organic functional groups is a promising technique for integrating the substrate's optoelectronic and surface capabilities with the molecular selectivity of the covering groups. As an example, functionalization of gold nanoparticles with amino acids such as lysine, polylysine, and glycine, among others, bind DNA more efficiently for gene delivery without creating any toxicity. Surface-functionalization first links nanoparticles with diverse organic and inorganic functionalities, then enhances nanoparticle solubility so that they can be utilised as carriers for hydrophobic species, and can be employed for uniform distribution in organic matrix. Surface functionalization can be accomplished through variety of methods that include post-functionalization, which is applied to already created inorganic nanoparticles, or in-situ functionalization, which is done during the synthesis process. Hydroxy-, thio-, amino-, nitro-, carboxy-, or primary alkyl groups, for example, are commonly used for tailoring surface functionality. Hydrophobic, hydrophilic, ionic, nonionic, van der Waal's, and hydrogen bond interactions are the basic working forces that lies behind functionalization.
Audience take-away:
- My presentation will give a comprehensive overview of nanoparticle synthesis, functionalization and characterization for various applications.
- With the knowledge of functionalization, various water soluble nanoparticles can be prepared and can be utilized for various purposes accordingly.
- Knowing how to functionalize, the synthetic process can be designed accordingly . Hope this will simplify their practical problems may improve their efficiency.
- With the help of the presentation , one may chalk out proper layout for designing functionalized nanoparticles.
