HYBRID EVENT: You can participate in person at Orlando, USA or Virtually from your home or work.

6th Edition of World Nanotechnology Conference

April 24-25, 2023

April 24 -26, 2023 | Orlando, USA
World Nano 2023

Sadia Afrin Khan

Sadia Afrin Khan, Speaker at Nanomaterials Conference
Food and Drug Administration, United States
Title : Characterization of nanoparticles in Silicon dioxide food additives


Food additives are substances intended to become a component or affect the characteristics of food (e.g., emulsifier, stabilizer, thickener, anticaking agent, antioxidant, etc.). Some food additives may have a particle size distribution that extends into the nanoscale range. For example, amorphous silicon dioxide, which is an approved direct food additive (21 CFR 172.480) for use as an anticaking agent may possibly contain nanosized silicon dioxide particles due to the nature of its manufacturing process. However, there are limited data concerning the particle size distribution of silicon dioxide used as a food additive. Therefore, we used multiple analytical techniques to characterize the particle size distribution of six commercially available silicon dioxide food additives. In this work, we used dynamic light scattering to measure particle size distribution, electron microscopy for imaging, and single-particle inductively coupled mass spectrometry (sp-ICP-MS) to measure the concentration of nano-sized materials present in silicon dioxide additives. These results allow the US FDA to gain a greater understanding of the potential for nano-sized particle occurrence in silicon dioxide intended for use as food additives.


Dr. Sadia Afrin Khan is a research scientist in the Center for Food Safety and Applied Nutrition (CFSAN) at the US Food and Drug Administration. Dr. Khan received her Ph.D. degree in Chemistry from Jackson State University in 2013. Her research interest includes analysis of nanomaterial, nanomaterial-based assay for toxin detection as well as characterization of nanoparticle in food additives. She has over twenty publications in high impact journals and cited no less than 2458 times.