Abstract
About this talk
The presentation will be focused on exploring mathematical models which are suitable to describe cargo-delivery using nanomaterials (NMs) while assessing information from in vitro assays. Presently, less than about 0.5% of the accumulated world’s reports involving in vitro assays include a mathematical model, but this fraction is growing up steeply worldwide in recent years, signaling the recent trend in handling the biological data in a more comprehensive way. The starting mathematical model for in vitro assays is the Hill equation, herein described as a Hill-inspired approach, characterized by its Hill coefficient. In this case, the morphological parameters of the NMs are included into the original Hill coefficient, which is interpreted as the number of ligand sites in the MNM’s surface which are available for binding to receptors onto the cell membrane.
Audience Take Away:
- Those producing and handling data from bioassays would be able to incorporate a more comprehensive analysis of the data
- The produced documents (reports, patents, papers) will incorporate a cutting edge approach, thus improving the technical and scientific standards
- The efficiency and technical quality of previsions will be enhanced
Speaker
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