HYBRID EVENT: You can participate in person at Rome, Italy or Virtually from your home or work.

10th Edition of World Nanotechnology Conference

March 10-12, 2025

March 10 -12, 2025 | Rome, Italy
World Nano 2024

Igor Reshetov

Igor Reshetov, Speaker at Nanoscience Conferences
Sechenov University, Russian Federation
Title : Photodynamic inactivation of antibiotic-resistant microflora using photosensitizer nanoforms


Purulent wounds treatment of soft tissues is associated with certain difficulties, which are caused by multiple factors, including occurrence, formation and wound nature specificities. Purulent complications significantly increase a treatment time and a process cost. We propose the problem solution of antibiotic-resistant microflora decontamination using technology based on fluorescent diagnostics and Photodynamic Inactivation (PDI). As nanocarriers, the photosensitizer ethosomes were used. Due to its neutral charge and spherical shape, the nanoparticles were able to penetrate through skin barrier and destroy pathogenic microorganisms.

70 patients were received PDI technology treatment of purulent wounds. Before and after irradiation, microflora composition and quantity were analyzed. The obtained data evidenced that local application of Photoran E6 and PDI technology inactivate both Gram-positive and Gram-negative bacteria. The use of photosensitizer nanocarriers led to obtain a quantitative decrease of bacterial growth in the wound of all patients and reduce the healing time of wounds.

PDI technology using application of photosensitizer nanocarriers showed high antimicrobial activity against antibiotic-resistant microflora of infected wounds in most clinical instances. The decontamination of microflora enabled to perform delayed reconstructive plastic surgery to close soft tissue defects and reduce hospitalization time of patients.

Audience Take Away:

  • An improvement of patients treatment was the main aim of study. The obtained information could be used as a part technologists and doctors studying
  • The results could help the audience in their job
  • Other faculties to expand their researches or teachings could use this research
  • This practical solution of the problem could simplify or make a designer’s job more efficient


Dr. Igor V. Reshetov studied medicine at the N.I.Pirogov Moscow Medical University University, USSR in 1987 and graduated as PhD in 1992. He then to the continued research in P.A.Herzen Cancer Research Institute, Moscow. After in same institute he defensed dissertation Doctor of Medicine in 1998 about microsurgical reconstruction organs and tissues in oncology , since 2014 he relocated in Sechenov University, Moscow  and in 2019 till now has position Director Institute cluster oncology. As a opinion lieder in field interdisciplinary access to treatment and rehabilitation in oncology associated in Russian Academy of Science in 2004 and in 2016 has full member of RAS . He has published more than 100 research articles in SCI(E) journals.) Index Hi 26.