Non-viral RNA delivery systems represent a promising avenue in nucleic acid therapeutics, offering distinct advantages in terms of safety and versatility. Unlike viral vectors, non-viral systems eliminate concerns related to immunogenicity and insertional mutagenesis. These systems encompass a spectrum of carriers, including lipid-based nanoparticles, polymeric nanoparticles, and lipid-polymer hybrid systems. Lipid-based nanoparticles, such as liposomes, have gained attention for their ability to encapsulate and protect RNA molecules. These nanostructures offer controlled release and enhanced cellular uptake. Polymeric nanoparticles, on the other hand, provide a stable platform for RNA delivery, with tunable properties for optimal payload protection and controlled release.
The versatility of non-viral systems extends to their potential for surface modification, allowing targeted delivery to specific cells or tissues. Surface engineering enhances the systemic circulation time and improves the overall pharmacokinetics of RNA therapeutics. Additionally, these systems can be fine-tuned for stimuli-responsive release, triggered by intracellular conditions. The development of non-viral RNA delivery systems addresses key challenges in the field, such as low transfection efficiency and potential safety concerns associated with viral vectors. Ongoing research focuses on optimizing these systems for clinical applications, ensuring efficient delivery of RNA molecules to target cells while minimizing off-target effects.
Therapeutics based on small interfering RNA (siRNA) have demonstrated tremendous potential for treating cancer. However, non-specific targeting, premature degradation, and intrinsic toxicity of the…
Participants can earn 1 CPD credit for each hour of attendance.
Oral and poster slots for original Non Viral RNA Delivery Systems work, reviewed by the scientific committee.
Meet nanotechnologists, researchers, scientists and engineers from around the world across three days.
In-person and virtual registrations include an electronic copy of the abstract book.
Plenary lectures from leading voices shaping Non Viral RNA Delivery Systems research and practice.
Attend in person in Singapore or join virtually — same programme, same certificate.
Oral and poster slots for your work — in person in Singapore or online. Not presenting? Attend as a delegate to learn from the field.
The Non Viral RNA Delivery Systems track is a dedicated stream within World Nano 2027 covering the latest research, innovation, and best practice in Non Viral RNA Delivery Systems. It brings together researchers, educators, and practitioners for oral presentations, posters, and discussion.
Nanotechnology researchers, scientists and engineers, educators and students with an interest in Non Viral RNA Delivery Systems are all welcome — whether presenting or attending.
Yes. Submit an abstract for oral or poster presentation. All submissions are peer-reviewed by the scientific committee.
Yes. World Nano 2027 is a hybrid conference — attend the Non Viral RNA Delivery Systems track in person in Singapore or join live online, with on-demand access afterward.
Singapore · March 18–20, 2027· Hybrid · in-person & virtual
Attend without presenting.
