Abstract
About this talk
Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundreds of FDA approved medical products. While nanomedicine has been around for several decades, new technological advances are pushing its boundaries. For example, this presentation will present an over 30 year journey of commercializing nanomaterials for orthopedic implants now in over 45,000 patients to date showing no signs of failure. Current orthopedic implants face a failure rate of 5 – 10% and sometimes as high as 60% for bone cancer patients. Further, this talk will present future research directions into using atomic layer deposition (ALD) to create such nanostructures on implants to reduce infection and improve bone growth. Sensors grown off of orthopedic implants using ALD will also be discussed in which cell presence on orthopedic implants can be detected and quantified. Such information can also be communicated to a handheld device to better inform surgeons on chances of implant success or failure. Such sensors can also release pharmaceutical agents and/or nanoparticles on-demand to ensure implant success. Lastly, this talk will cover how Artificial Intelligence (AI) can be combined into today’s orthopedic implants to predict implant success or failure in the years that follow.
Speaker
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